Rapid Detection of Anti-IFN-α2 Autoantibodies Using a New Automated VIDAS Assay Prototype.
Autoantibodies neutralizing Type I interferons increase the risk of severe viral diseases and are linked to autoimmune conditions. The automated VIDAS assay is suitable for anti-IFN-α2 IgGs quantification, offering a swift, reliable, user-friendly, single test for clinical management.
DOI: 10.1002/eji.202451516, PMID: 40223598
Authors: Sylvie Pons, Laurence Generenaz, Adrian Gervais, Anne Puel, Paul Bastard, Nathalie Renard, Valerie Guyot, Cecile Vinit, Fei Zheng, Karen Brengel-Pesce, Kahina Saker, Jean-Christophe Richard, Alexis Mathian, Zahir Amoura, Karim Dorgham, Guy Gorochov, Jean-Laurent Casanova, Aurore Fleurie, Sophie Trouillet-Assant