Ancient DNA as a tool for medical research.

1 May 2023 Publications

No abstract available

DOI: 10.1038/s41591-023-02244-4, PMID: 36922577
Authors: Gaspard Kerner, Jeremy Choin, Lluis Quintana-Murci

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia.

Other articles

Publications 2 March 2026

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis.

Fulminant viral hepatitis (FVH) is a devastating condition caused by hepatotropic viruses such as hepatitis A virus (HAV), hepatitis B virus (HBV), and HSV-1/2. We studied 149 FVH patients (73 males and 76 females, aged 1-76) for blood autoantibodies (auto-Abs) [...]

Publications 2 March 2026

Expanding the scope of human immunology in the .

The publishes molecular, cellular, and clinical studies of patients with inborn errors of immunity, or their phenocopies, including autoimmune and somatic disorders. A central tenet in the field is that the current range of genetic immunological disorders is only [...]

Publications 2 March 2026

Autoantibodies neutralizing type 1 interferons in two cohorts of people with HIV.

Autoantibodies (autoAbs) neutralizing type I interferons (IFN-I) markedly increase the risk of severe manifestations of some viral diseases. The prevalence of autoAbs neutralizing at least one IFN-I, specifically IFN-α2, IFN-β, and IFN-ω, in individuals from the Swiss human immunodeficiency virus [...]

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